The urea cycle functions to incorporate ammonia, generated by normal metabolism, into urea.Urea cycle disorders (UCDs) are caused by loss of function in any of the enzymes responsible for ureagenesis, and are characterized by life-threatening episodes of acute metabolic decompensation with hyperammonemia (HA).A prospective analysis of interim HA ev

Abstract Paleoclimate records have been used to estimate the modern equilibrium climate sensitivity.However, this requires understanding how the feedbacks governing the climate response vary with the climate itself.Here we warm and cool a state-of-the-art climate model to simulate a continuum of climates ranging from CAPA Pillows a nearly ice-cover